How Artificial Sweeteners Alter Gut Bacteria in Humans? Experts Answer


Changes in gut microbiota composition due to artificial sweeteners may have metabolic effects

Although they are generally considered safe for consumption, research has shown that artificial sweeteners can affect gut bacteria in humans.

Artificial sweeteners are sugar substitutes that are used as a low-calorie or zero-calorie substitute for sugar in a wide range of foods and beverages. Although they are generally considered safe for consumption, research has shown that artificial sweeteners can affect the gut bacteria, also known as the gut microbiota, in humans.

Dr. Richa Chaturvedi, Senior Consultant, Endocrinology, Apollo 24|7 and Indraprastha Apollo Hospital, New Delhi, says, “Artificial sweeteners have been shown to affect the makeup and function of the gut flora. According to research, saccharin, aspartame and Sweeteners such as sucralose can alter the gut microbiota, creating an imbalance in the type and number of beneficial bacteria. This disruption can affect a variety of metabolic processes and lead to obesity, glucose intolerance, and altered metabolism. can lead to diseases such as the satiety response. While the specific mechanisms are still being investigated, it is important to evaluate the potential influence of artificial sweeteners on gut health and general well-being, particularly in those with For those with underlying metabolic disorders.

Research shows that consuming artificial sweeteners can lead to changes in the abundance and diversity of gut bacteria. Some studies have seen an increase in certain bacteria, such as Bacteroides and Proteobacteria, while others have seen a decrease in beneficial bacteria such as bifidobacteria. Changes in gut microbiota composition due to artificial sweeteners may have metabolic effects.

By: Ankita Ghoshal Bisht, Dietitian, Primus Super Specialty Hospital, New Delhi, says, “According to research, artificial sweeteners can convert healthy gut bacteria into pathogens and hence affect gut health. Study showed that sweeteners increase the ability of bacteria to form biofilms. Bacteria that grow in biofilms are less susceptible to antimicrobial resistance treatments. They secrete toxins and express disease-causing molecules. All gut microbiota contain two types of gut bacteria: E. coli and E. faecalis. When exposed to artificial sweeteners, these gut bacteria can become pathogenic (disease-causing). Capacity increases.”

It is important to note that the effects of artificial sweeteners on gut bacteria may vary among individuals. Factors such as genetics, diet, and baseline gut microbiota composition may influence how different people respond to these sweeteners.

Although artificial sweeteners are generally considered safe for consumption, they can affect the composition and function of the gut microbiota in humans. More research is needed to fully understand the extent of these effects and their impact on human health.



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